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Ashwagandha (Withania): An adaptogen that reduces

Ashwagandha (Withania): An adaptogen that reduces oxidative stress and promotes overall reproductive health.

Turmeric: Contains curcumin, a potent antioxidant and anti-inflammatory compound that protects against DNA damage

Milk Thistle: Contains silymarin, an antioxidant that protects cells from toxins and oxidative stress.

Rosemary is rich in antioxidants, particularly rosmarinic acid and carnosic acid, which help protect cells from oxidative stress and DNA damage. These antioxidants neutralize free radicals, reducing the risk of DNA fragmentation and supporting overall cellular health.

Green Tea: Rich in catechins, particularly EGCG, which has strong antioxidant properties and can protect DNA from oxidative damage.

Folate and B12 support DNA synthesis and repair.

Vit C & E: antioxidants protecting DNA from damage

Vitamin D: Supports DNA repair mechanisms and modulates the immune response, which can help reduce inflammation and oxidative stress that lead to DNA damage

Alpha-lipoic acid (ALA): Acts as a universal antioxidant, protecting cells from oxidative stress by neutralizing free radicals. It also regenerates other antioxidants, such as vitamins C and E, enhancing overall cellular protection and reducing DNA damage.

Lycopene: A powerful carotenoid found in tomatoes and other red fruits, lycopene has strong antioxidant properties that protect DNA from oxidative damage. It helps maintain the integrity of cells and supports overall cellular health, reducing the risk of DNA fragmentation.

Selenium: Acts as an antioxidant, protecting DNA from oxidative damage and reducing DNA fragmentation

Zinc: Essential for DNA synthesis and repair, zinc stabilizes the DNA structure and enhances the activity of DNA repair enzymes

Coenzyme Q10 (CoQ10): Functions as a powerful antioxidant, protecting cells from oxidative stress and DNA damage.

Some men just won’t. Don’t. Can’t. For whate

Some men just won’t. Don’t. Can’t. For whatever reason.

So get him to do a blood test for MTHFR & homocysteine.

60% of us have an MTHFR defect which then drives homocysteine.

Homocysteine causes sperm DNA fragmentation.

Ideally homocysteine should be between 7-9. Lab range is usually 5-15. Once I see it above 10, it’s too high, and we’ll start working on DNA 🧬 and sperm quality.

In a semen analysis, DNA fragmentation needs to be requested additionally. A standard semen analysis includes count, motility and morphology. DBA frag and anti-sperm antibodies are “optional extras”. 🤦‍♀️

I want the DNA frag to be excellent, meaning a low percentage. The range is 5-15% frag is considered excellent. I want it ideally below 10% (as low as possible)

It’s best if they do both- semen analysis with DNA fragmentation AND blood test for MTHFR with homocysteine.

Sperm DNA fragmentation severely affects fertility

Sperm DNA fragmentation severely affects fertility, conception, implantation and has a causal relationship with early pregnancy loss and miscarriage (I hate that word soooooo much. No one in the history of #ttc has ever intentionally mis-carried their baby. Ridiculous concept)

Male fertility matters, and male sperm health issues cause early pregnancy loss. Just because she physically experiences it, he can be the WHY.

Unfortunately, DNA frag is not tested on standard semen analysis. Count, motility and morphology are all tested, but DNA frag (and anti-sperm antibodies for that matter) are added on extras. FFS.

And it’s not cheap. FFS.

But it’s worth it.

And nothing pisses me off more than a woman being told “once you have 3 miscarriages, then we’ll investigate”. WTAF.

One early pregnancy loss is enough for any soul to bear.

Do the testing. Do all the testing. Before you conceive.

15 different nutrients are required for healthy sp

15 different nutrients are required for healthy sperm. 15. Take the damn male prenatal.

➡️The acrosome is a cap-like structure derived from the Golgi apparatus that covers the anterior portion of the head of a sperm cell. It plays a crucial role in fertilization by containing enzymes that help the sperm penetrate the outer layers of the egg (oocyte).
✅It needs calcium:
The acrosome reaction is triggered by an influx of calcium ions (Ca²⁺) into the sperm cell when it comes into contact with the egg’s zona pellucida. This influx is essential for the fusion of the acrosomal membrane with the sperm’s plasma membrane, leading to the release of acrosomal enzymes that help the sperm penetrate the egg.

➡️ The Head & DNA in the nucleus require: bucket loads of antioxidants- A, C, E, zinc, selenium, CoQ10, alpha lipoic acid, lycopene (these are what is needed if there is a DNA fragmentation issue), vitamin D, folate, B12, arginine

➡️The Neck & Mid Piece: zinc, vitamin D, CoQ10

➡️The Tail: selenium (this helps motility)

➡️The entire structure: Protein, EFS’s and Vitamin E

‼️A semen analysis looks at morphology- the shape of the sperm. 4% normal shape is the bench mark ;that means it normal to have 96% abnormally shaped sperm… WTAF.
Some of the reports (not all labs do this)will break it down to where the majority of the faults lie within the structure of the sperm- the head, tail or neck piece which can be handy.
Even if your report doesn’t detail precisely where, it is enough to know low morphology to accurately direct treatment.

I hate the word miscarriage. No one (man or woman)

I hate the word miscarriage. No one (man or woman) mis-carries their baby. “I carried my baby the wrong way”. What a ridiculous concept.

And of course, because it is the woman that miscarries, then it’s on her, right?

Wrong.

Firstly, it’s early pregnancy loss. And it’s devastating.
Secondly, it’s no one’s fault. No one is to blame.

I am writing this not to lay blame. There are many factors that contribute to early pregnancy loss.

But I think one little known factor is the role sperm DNA fragmentation plays in early pregnancy loss.

The only job of the sperm really is to deliver its DNA to the egg. Thats what creates an embryo.
An embryo is 50% egg and 50% sperm, so “egg quality” only accounts for half of the embryo quality. The other half is sperm quality and DNA fragmentation affects that quality.

The DNA is on the head of the sperm and it is quite normal to have some of it damaged/broken/fragmented.

If that fragmentation levels is between 5-15% that is considered excellent DNA frag.
15-20% = good
20-25% = fair
> 25% = poor
The higher the fragmentation, the poorer the quality of the DNA, and more it affects the quality of the embryo. Poor DNA fragments can affect conception, implantation and is responsible for early pregnancy loss.
I shared someone else’s reel about DNA fragmentation being responsible for “most miscarriages”. I’m not sure about most, but I certainly think * many, many, many*

Again, this is not a blame thing. It’s an awareness thing.

Awareness of the impact sperm fragmentation can have.

Awareness of semen analysts testing that looks at DNA frag.

And awareness that even if it is high, it can be fixed (otherwise there’s no point creating if we can’t do anything about it. That’s just fear mongering).

High levels of DNA fragmentation can be fixed. In a nutshell, it’s about bucket loads of antioxidants, removing EDC’s, chemicals and toxins.

I’ll post more about this x

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